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Ten Facts About DMSO

Am learning more about DMSO, which was publicized as a "cure all" in the '60s, then banned by FDA and at some point "unbanned." I remember my mom talking about it, as she was into the whole "health foods" thing back then.

I'm trying a pain relief creme with a mix of DMSO, magnesium, and other "stuff." It seems to work pretty well. Wondering if I can do direct DMSO...

Ten facts:

    1. Chemical Composition

    DMSO is an organosulfur compound with the formula (CH₃)₂SO. It’s a colorless liquid known for its distinct garlic-like odor.

    2. Solvent Properties

    It’s an excellent solvent for both organic and inorganic compounds, often used in chemical reactions and pharmaceutical preparations due to its ability to dissolve a wide range of substances.

    3. Topical Application

    DMSO is commonly used topically in medical settings, particularly for treating pain and inflammation. It’s quickly absorbed through the skin, allowing it to act on targeted areas effectively.

    4. Analgesic and Anti-inflammatory

    DMSO has notable analgesic (pain-relieving) and anti-inflammatory properties, which is why it’s widely used in sports medicine and veterinary applications.

    5. Carrier Ability

    DMSO enhances the absorption of other substances through the skin, making it a popular "carrier" for certain medications and therapeutic agents.

    6. FDA-Approved Use

    Although DMSO has multiple applications, it is FDA-approved only for interstitial cystitis (a chronic bladder condition), where it is administered directly into the bladder.

    7. Controversial History

    DMSO gained attention in the 1960s as a potential wonder drug, but concerns over side effects, particularly issues with vision, stalled its widespread approval for many conditions.

    8. Low Toxicity

    DMSO is considered relatively safe with low toxicity when used properly. However, high concentrations or improper use can cause side effects such as skin irritation and a garlic taste or odor on the breath and skin.

    9. Industrial and Laboratory Use

    Beyond medical applications, DMSO is widely used in industrial and laboratory settings as a polar aprotic solvent, particularly valuable in organic synthesis and cell cryopreservation.

    10. Antioxidant Properties

    It has potential as an antioxidant, as some studies suggest that DMSO can scavenge free radicals and help reduce oxidative stress, though more research is needed to confirm these effects in humans.

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